| Abstrakt: |
THE EXISTENCE of hypogonadism with anosmia was first described in an autopsy case in 1856 by Maestre de San Juan.1 In 1944, Kallmann et al2 suggested sex-linked inheritance of hypogonadotropic hypogonadism with anosmia and noted occurrence of harelip, cleft palate, and craniofacial asymmetry. Since then, other clinical cases associated with various skeletal, ophthalmic, urogenital, and cardiovascular abnormalities have been reported.3-5This article reports an association of Kallmann's syndrome with atrial septal defect (ASD)-type ostium secundum.Report of a CaseA 22-year-old male student was admitted to our clinic because of great concern about his small penis and inadequate masculinization. He had never shaved or ejaculated. There was a history of lifelong insensitivity to common odors but no family history of hypogonadism, sterility, anosmia, or cardiovascular disorder.Physical examination showed a eunuchoidal man with some increased adipose tissue over the abdomen and hips. His height was 173 cm |
