Colocalization of fructose-1,6-bisphosphatase and glial fibrillary acidic protein in rat brain

Autor: Schmoll, Dieter, Cesar, Marija, Führmann, Elgin, Hamprecht, Bernd
Zdroj: Brain Research; April 1995, Vol. 677 Issue: 2 p341-344, 4p
Abstrakt: Immunofluorescence studies of rat brain sections demonstrated an exclusive colocalization of the gluconeogenic key enzyme fructose-1,6-bisphosphatase (FBPase) with the astroglial marker glial fibrillary acid protein, indicating FBPase in brain as an astrocyte-specific enzyme. This conclusion was supported by the presence of FBPase activity in astroglia-rich but not neuron-rich primary cultures derived from rat brain.
Databáze: Supplemental Index