Changes in the Synovial Fluid Caused by Osmic Acid

Autor: Lörincz, G., Isomäki, H. A., Martio, J.
Zdroj: Scandinavian Journal of Rheumatology; 1970, Vol. 16 Issue: 1 p217-222, 6p
Abstrakt: 27 rheumatic patients with knee joint hydrops were studied for the effect of osmic acid on the synovial fluid. Special interest was taken in synovial leucocyte counts and electrophoretic patterns. A leucopenia preceded the leucocytosis in the synovial samples; both were thought to be induced by osmium. A precipitate formation from hyaluronate was thought to account for the leucopenia and this suggests a new hypothesis of osmic acid action. In the electrophoretic patterns there was a change in the electric charges of proteins. One week after osmic acid injection the pattern was normal.
Databáze: Supplemental Index