Preliminary studies on the development of a swine vesicular disease vaccine

Autor: Mowat, G. N., Prince, M. J., Spier, R. E., Staple, R. F.
Zdroj: Archives of Virology; December 1974, Vol. 44 Issue: 4 p350-360, 11p
Abstrakt: Summary The work reported is concerned with the production of swine vesicular disease virus, its inactivation and the immunogenicity of vaccines prepared from it for pigs. The virus can be grown in either monolayer or suspension cultures of IB-RS-2 cells. Virus titres of 108.5 to 109.0 p.f.u./ml have been obtained regularly in both systems in approximately 24 hours. At present the monolayer system would be used for the large-scale production of virus.
Databáze: Supplemental Index