Cyclization of isoprenoid compounds

Autor: Muntyan, G. E., Mortikova, E. I., Smit, V. A., Semenovskii, A. V., Kucherov, V. F.
Zdroj: Russian Chemical Bulletin; August 1969, Vol. 18 Issue: 8 p1678-1682, 5p
Abstrakt: 1.The cyclization reaction of cis- and trans-1-(a-monocyclofarnesyl)-2-acetoxypropanes (IX) upon reaction with H2SO4 leads with good yield to 1-(cis-A/B-ß-bicyclofarnesyl)-2-acetoxypropane (X) with an admixture (up to 20%) of the? isomer (Xa). Upon carrying out this reaction with BF3 etherate the content of the?-isomer in the mixture is increased to 50%.2.Under analogous conditions cyclization of cis- and trans-1-(ß-monocyclofarnesyl)-2-acetoxypropanes (XI) proceeds more complexly and cannot serve as a preparative method of obtaining the corresponding bicyclic systems of the trans-decalin series.
Databáze: Supplemental Index
načítá se...