| Abstrakt: |
Reaction of 1-phenethyl- and 1-methoxycarbonylethylaziridine with 2,3-dimercaptopropanol gives the corresponding N-substituted (4-hydroxymethyl-1,8-diamino)-3,6-dithiaoctanes. Reaction of aziridine and Us 1-substituted derivatives with 2,3-dimercaptopropanesulfonic acid gives the corresponding [1,10-diamino-3-oxa-4, 8-dithia-6-(2-aminoethylthio)]decane-4,4-dioxides. Treatment of them with sodium bicarbonate produces the corresponding sodium 2,3-bis(2-aminoethylthio)propanesulfonates. Cyclocondensation of certain synthesized diamines with adipic diazide produces 16-membered macroheterocycles with exocyclic methoxycarbonylethyl, hydroxy-, or sulfonatomethyl groups. |
Full text from SpringerLink