Autor: |
Courtoy, R., Boniver, J., Simar, L. J. |
Zdroj: |
Histochemistry and Cell Biology; January 1980, Vol. 66 Issue: 1 p49-58, 10p |
Abstrakt: |
The modifications of mouse mast cells incubated in solutions of polylysine at two different concentrations are studied. At higher dose (0.5 mg/ml), the polycation has evident toxic effects. At lower dose (0.5 µg/ml), it induces some modifications of the granule morphology. Cytochemical reactions to demonstrate polyanions, basic proteins and organic bases are used to study the granule content. A polylysine treatment promotes the release of basic groups (vaso-amines) and sulphydryl-containing compounds (basic protein) from the mast cell granules. On the contrary, polyanions remain in the cells and correspond to the granule matrix persisting after amino-liberator treatment. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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