Diffusion in HPMC Gels. II. Prediction of Drug Release Rates from Hydrophilic Matrix Extended-Release Dosage Forms

Autor: Gao, Ping, Nixon, Phillip R., Skoug, John W.
Zdroj: Pharmaceutical Research; July 1995, Vol. 12 Issue: 7 p965-971, 7p
Abstrakt: Purpose. A mathematical model is described for the prediction of the relative change in drug release rate as a function of formulation composition for HPMC-based extended-release (ER) tablets of adinazolam mesylate and alprazolam.
Databáze: Supplemental Index