Urinary androgen and 17-hydroxylated corticosteroid metabolites and their relation to recurrence rates in early breast cancer

Autor:	Thomas, Brian S., Bulbrook, Richard D., Russell, Martin J., Hayward, John L., Millis, Rosemary R.
Zdroj:	Breast Cancer Research and Treatment; March 1984, Vol. 4 Issue: 1 p27-35, 9p
Abstrakt:	Summary The amounts of urinary androsterone and etiocholanolone are highly correlated with recurrence rates in patients with early breast cancer after treatment by mastectomy. A more efficient means of predicting the clinical course of the disease is obtained by using a ratio of these compounds to the amounts of individual 17-hydroxycorticosteroids in the urine. For instance, the ratio of androsterone to a-cortolone is particularly effective in identifying women with a high rate of recurrence, and this is largely independent of pathological stage and tumor grade.
Databáze:	Supplemental Index
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