Activity of Carbetimer in a human tumor cloning system

Autor: Kisner, Daniel L., Mehta, Persis, Paget, G. Edward, Hoff, Daniel D.
Zdroj: Investigational New Drugs; March 1984, Vol. 2 Issue: 1 p55-58, 4p
Abstrakt: The antitumor activity of Carbetimer was tested against 171 patient's tumors in a human tumor cloning system. Sixty-seven tumor specimens had adequate growth to be considered evaluable. In 21 specimens survival of tumor colony forming units was =50% that in control plates. Antitumor effect was most impressive in carcinomas of the breast, ovary, and lung. This information will be useful in planning disease oriented Phase II trials.
Databáze: Supplemental Index