Effects of ATP and UTP in pheochromocytoma PC12 cells: Evidence for the presence of three P2 receptors, only one of which subserves stimulation of norepinephrine release
| Autor: | Nikodijevic, Branislav, Sei, Yoshitatsu, Shin, Yangmee, Daly, John W. |
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| Zdroj: | Cellular and Molecular Neurobiology; February 1994, Vol. 14 Issue: 1 p27-47, 21p |
| Abstrakt: | Summary 1. In pheochromocytoma PC12 cells ATP and, to a lesser extent, 2-methylthioATP stimulate phosphoinositide breakdown, release of intracellular calcium, and influx of external calcium, leading to stimulation of norepinephrine release. In contrast, although UTP also stimulates phosphoinositide breakdown, release of intracellular calcium, and influx of external calcium, there is no stimulation of norepinephrine release. |
| Databáze: | Supplemental Index |
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