| Autor: |
Lafon, Earl E., Pohl, Herbert A. |
| Zdroj: |
Journal of Biological Physics; December 1981, Vol. 9 Issue: 4 p209-217, 9p |
| Abstrakt: |
It is increasingly recognized that exposure to electrical fields can reversibly increase the electrical permeability and conductivity of the cellular membrane. It is therefore worthwhile to determine under what circumstances the critical fields capable of affecting the cellular membrane can be reached. We have evaluated the field intensities E and the gradients of E2 in the neighborhood of the more common field electrode shapes, the sphere-sphere and cylinder-cylinder electrodes, and put these in terms of the values useful for the practical electro-fusion and dielectrophoresis (DEP) of cells. The calculations were performed using the charge-image technique. From this it was observed that gross errors (underestimations of up to 1000-fold) of the field would be made if neglect of the electrode polarization were made as in simple electrostatic calculation. The dielectric forces (in terms of ▽(E)2) show interesting spatial character. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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