| Autor: |
Baldwin, S. W., Chen, P., Nikolic, N., Weinseimer, D. C. |
| Zdroj: |
Organic Letters; May 2000, Vol. 2 Issue: 9 p1193-1196, 4p |
| Abstrakt: |
A protocol for achieving stereoselective aldol reactions with cyclic ketones is presented. In terms of yield, the process is particularly effective when a quaternary center at the α-carbon of the β-hydroxy ketone product is created. The stereochemical outcome, anti or syn, is achieved by the Lewis acid-mediated ring expansion of stereochemically homogeneous epoxides in a reaction related to the pinacol rearrangement. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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