Discovery of a Brain-Penetrant S1P3-Sparing Direct Agonist of the S1P1and S1P5Receptors Efficacious at Low Oral Dose.
Autor: | Demont, Emmanuel H., Arpino, Sandra, Bit, Rino A., Campbell, Colin A., Deeks, Nigel, Desai, Sapna, Dowell, Simon J., Gaskin, Pam, Gray, James R. J., Harrison, Lee A., Haynes, Andrea, Heightman, Tom D., Holmes, Duncan S., Humphreys, Philip G., Kumar, Umesh, Morse, Mary A., Osborne, Greg J., Panchal, Terry, Philpott, Karen L., Taylor, Simon |
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Zdroj: | Journal of Medicinal Chemistry; Oct2011, Vol. 54 Issue 19, p6724-6733, 10p |
Databáze: | Supplemental Index |
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