| Autor: |
Nishigaki, Kazuhiko, Yamazaki, Tsutomu, Kitabatake, Akira, Yamaguchi, Tetsu, Kanmatsuse, Katsuo, Kodama, Itsuo, Takekoshi, Noboru, Tomoike, Hitonobu, Hori, Masatsugu, Matsuzaki, Masunori, Takeshita, Akira, Shimbo, Takuro, Fujiwara, Hisayoshi |
| Předmět: |
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| Zdroj: |
JACC: Cardiovascular Interventions; Oct2008, Vol. 1 Issue 5, p469-479, 11p |
| Abstrakt: |
Objectives: This study sought to determine whether initial medical therapy (MT) only or percutaneous coronary intervention plus medical therapy (PCI+MT) is better for patients with low-risk stable coronary artery disease (CAD) indicated for intervention in Japan. Background: Several multicenter studies have suggested that in the above patients, an initial management strategy of PCI+MT does not reduce the long-term risk of cardiovascular events more effectively than initial MT only. Methods: We conducted a randomized comparative study (JSAP [Japanese Stable Angina Pectoris] study) in the previously mentioned patients. Results: The patients were randomized to PCI+MT (n = 192) or initial MT only group (n = 192), and the patient characteristics were very similar in the 2 groups. During the 3.3-year follow-up, there was no significant difference in the cumulative death rate between PCI+MT (2.9%) and MT (3.9%). However, the cumulative risk of death plus acute coronary syndrome was significantly smaller in PCI+MT. Conclusions: In stable low-risk CAD, PCI+MT may improve long-term prognosis more effectively than MT. [Copyright &y& Elsevier] |
| Databáze: |
Supplemental Index |
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