Autor: |
Cooper, David K. C., Miller, Leslie W., Patterson, G. Alexander, Federspiel, W., Sawzik, P., Borovetz, H., Reeder, G. D., Hattler, B. G. |
Zdroj: |
Transplantation & Replacement of Thoracic Organs; 1996, p717-728, 12p |
Abstrakt: |
The adult respiratory distress syndrome (ARDS), described first by Ashbaugh and his colleagues[1] almost 30 years ago, continues to present a dilemma to the clinician, for the mortality associated with the syndrome has remained exceedingly high in spite of a better understanding of the mechanisms that contribute to this pulmonary disease process. For the patient with ARDS, maintaining gas exchange at a level consistent with survival is associated frequently with progressively increasing levels of respiratory support. The final outcome in these patients is contributed to not only by the degree of pulmonary injury, but also by the level of dysfunction in multiple other organs=. Recognizing these facts, and that any therapy for ARDS involves more than just providing a setting where the lungs have the potential for recovery, we will concentrate this discussion on new therapies with intracorporeal devices under development for the treatment of ARDS. [ABSTRACT FROM AUTHOR] |
Databáze: |
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