Breeding and Genotyping of Tfam Conditional Knockout Mice.

Autor: Walker, John M., Copeland, William C., Ekstrand, Mats, Larsson, Nils-Göran
Zdroj: Mitochondrial DNA; 2002, p391-400, 10p
Abstrakt: Respiratory chain dysfunction is an important contributor to human pathology (1-3). The generation of animal models has much facilitated in-depth studies of pathogenetic mechanisms in mitochondrial disease (4). The function of the respiratory chain is subject to the dual genetic control of both the nuclear and mitochondrial genomes (1). [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index