SUBGEMMAL NEUROGENIC PLAQUE IN A 40-YEAR-OLD WOMAN.

Autor: MIRANDA, Ana Paula Ribeiro, de SOUZA, Vitória Iaros, de CASTRO, Tamara Fernandes, FURUSE, Cristiane, MIYAHARA, Glauco Issamu, VALENTE, Vitor Bonetti, BERNABÉ, Daniel Galera
Zdroj: Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Jun2024, Vol. 137 Issue 6, pe244-e244, 1p
Abstrakt: Subgemmal neurogenous plaque is a regional anatomic variation characterized by the presence of ganglion cells in a subepithelial nerve plexus close to the taste buds of the tongue. A 40-year-old female patient was referred for evaluation due to a burning sensation on the right lateral border of her tongue, which had been bothering her for the past 9 months. Upon intraoral examination, an erythematous area and hyperplastic foliate papillae were observed on the left lateral border of her tongue. The initial diagnostic considerations included foliate papillitis and subgemmal neurogenic plaque. Subsequently, the lesion was surgically removed, and a histopathological examination, along with immunohistochemical staining for S100, was conducted. Microscopically, the lesion exhibited a superficial layer that resembled a neurofibroma-like proliferation running parallel to the surface epithelium, and a deeper area composed of tortuous neuronal bundles with ganglion cells, similar to a neuroma-like lesion. This supported the diagnosis of subgemmal neurogenic plaque. The patient remained asymptomatic at a 9-month follow-up. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index