| Abstrakt: |
A study conducted by researchers at Guangdong Food & Drug Vocational College in Guangzhou, China, aimed to investigate the therapeutic mechanism of Hengqing II decoction in treating Alzheimer's disease (AD) using network pharmacology and molecular docking techniques. The study characterized the major chemical compounds of Hengqing II decoction and collected gene sets related to AD treatment. A molecular network was constructed, and enrichment analysis was performed to predict the potential active compounds and targets of Hengqing II decoction for treating AD. The study concluded that Hengqing II decoction exerts therapeutic effects on AD through multi-component, multi-target, and multi-pathway regulation, with action mechanisms related to oxidative stress, neuroinflammation, autophagy, and other pathways. This research provides a foundation for further exploration of the action mechanism and clinical positioning of Hengqing II decoction in TCM formula research. [Extracted from the article] |
