Synthesis and structural characterization of benzene-1,3- disulfonamide-containing 11- to 13-membered heterocycles via double Mitsunobu annulation.

Autor: Kyosuke Kaneda, Takato Koideya, Ryuji Toshima, Yoshiki Konno, Takehiro Yamagishi
Zdroj: Chemistry Letters; Jan2024, Vol. 53 Issue 1, p1-4, 4p
Abstrakt: The synthesis and 3D-conformation of several novel benzene-1,3-disulfonamides-containing 11- to 13-membered heterocycles have been achieved. Double Mitsunobu annulation was effective for the construction of medium to large ring systems in moderate chemical yields. In addition, the flexibility of sulfonamide moieties in these rings was determined by X-ray crystal structural analysis. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index