| Autor: |
Napier-Hemy, Timothy P, Feyisetan, Oladapo, Stewart, Heather, Chamsin, Alaa, Floyd Jr, Michael S, Samsudin, Azizan, Omar, Ahmad M |
| Zdroj: |
Journal of Clinical Urology; Mar2023, Vol. 16 Issue 2, p91-95, 5p |
| Abstrakt: |
Objectives: To determine whether administration of single dose prophylactic intravenous gentamicin prior to intravesical injection of botulinum toxin type A (BoNT-A) is associated with adverse extravesical neuromuscular effects in idiopathic overactive bladder syndrome. Patients and methods: A retrospective analysis of 220 consecutive idiopathic overactive bladder patients following sedation-free flexible cystoscopic injection of intravesical BoNT-A. All patients received a single dose of intravenous gentamicin (160 mg) followed by 100-200 IU of BoNT-A. They were followed up at intervals to determine whether they had experienced any adverse extravesical neuromuscular side effects. Results: None of our patients developed adverse extravesical neuromuscular side effects from intravesical botulinum injections with concomitant administration of intravenous gentamicin. Conclusion: Single dose intravenous gentamicin is safe to use as a prophylaxis for intravesical BoNT-A injections of 200 IU or below in idiopathic overactive bladder patients. Level of evidence: Not applicable. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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