| Autor: |
Soaida, Sherif Mohamed, Hafez, Mohamed EL-Saied, Girgis, Karim Kamal, Marie, Mohamed Mahmoud, Selim, Mohamed Ahmed |
| Zdroj: |
Egyptian Journal of Anaesthesia; Dec2022, Vol. 38 Issue 1, p476-482, 7p |
| Abstrakt: |
This study was carried out to compare different routes of midazolam administration (nebulized vs. oral) to achieve a satisfactory level of sedation, RAMSAY Sedation Score (RSS) of 4, within 30 minutes of midazolam administration in pediatric operative patients. After approval of the ethical committee in Kasr Al-ainy university hospital and obtaining written consent from parents/legal guardians; Seventy-two pediatric patients scheduled for general and urological surgical operations under general anesthesia were included in this randomized double-blinded study. Patients were randomly assigned into one of the two equal groups. Group N: 36 children received nebulized midazolam 0.2 mg/kg in 3 ml normal saline plus 5 ml clear juice 30 min before undergoing general anesthesia (GA). Group O: 36 children received oral midazolam 0.5 mg/kg in 5 ml clear juice plus nebulizer of 3 ml normal saline 30 min before undergoing general anesthesia. We found no statistical difference between nebulized and oral midazolam regarding drug acceptance, peri-operative (sedation scores, hemodynamics, and side effects); P-value >0.05 for all values. Nebulized midazolam is a good alternative to oral midazolam as a sedative premedication in pediatrics. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
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