| Autor: |
Oliveira, Arthur Lemos, Coutinho, Bruna Das Graças Miranda, De Oliveira Silva, Alice Maria, Pires, Fábio Ramôa, De Castro Lara, Shimelly Monteiro, De Barros Dias, Bruno Santos, Calcia, Thayanne Brasil Barbosa |
| Zdroj: |
Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Sep2022, Vol. 134 Issue 3, pe143-e143, 1p |
| Abstrakt: |
A 15-year-old boy was referred for evaluation of radiolucent lesions associated with bilateral impacted third molars. Clinical exam revealed cortical expansion of maxilla. Panoramic imaging and computed tomography showed bilateral involvement of the maxillary sinus and smaller mandibular lesions. Mandibular lesions were managed through enucleation plus osteotomy and maxillary lesions were decompressed. Histological analysis of hematoxylin and eosin–stained slides from all lesions revealed a cystic cavity lined by parakeratinized stratified squamous epithelium and a well-defined basal cell layer with polarized nuclei in palisade, confirming the diagnosis of odontogenic keratocyst. Nevoid basal cell carcinoma syndrome (NBCCS) was suspected but other features of the syndrome, such as bifid ribs, falx cerebri calcification, and cutaneous lesions, were not identified after careful medical analysis. Genetic investigation is in progress. The patient is under clinical and radiological follow-up. Thus, we report a case of multiple keratocysts possibly not associated with NBCCS or presenting as the sole and first manifestation of the disease. [ABSTRACT FROM AUTHOR] |
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