| Autor: |
De Almeida Lima Borba Lopes, Amanda, De Souza Vieira, Gustavo, Silva, Arley, Milagres, Adrianna, Rozza-De-Menezes, Rafaela Elvira, Cunha, Karin Soares Gonçalves, Conde, Danielle Castex |
| Zdroj: |
Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Sep2022, Vol. 134 Issue 3, pe108-e109, 2p |
| Abstrakt: |
Sjögren's syndrome is a chronic autoimmune disease, and Küttner tumor is a benign inflammatory condition. Both affect the salivary glands and are rarely associated. A 48-year-old Black woman complained of bilateral submandibular salivary gland enlargement, xerostomia, and xerophthalmia for approximately 7 months. Sialometry revealed severe hyposalivation. An ultrasound examination performed 4 months after the onset of symptoms showed a solid hypoechogenic nodule of 20 mm in the left submandibular salivary gland. An incisional biopsy demonstrated a chronic sclerosing sialadenitis (Küttner tumor) with only 10% positivity for IgG4+ plasma cells, ruling out the diagnosis of IgG4-related disease. Serologic exam for anti-SSA/Ro antibody was highly reactive (200.0 U/mL). Labial salivary glands were excised, and the histopathologic exam revealed a focal lymphocytic sialadenitis, confirming the diagnosis of Sjögren's syndrome. Prednisone (40 mg) and methotrexate (15 mg) were administered for 1 month, with symptom improvement and clinical reduction of the volume of the Küttner tumor. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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