Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose.
| Autor: | Lingtian Zhang, Moccia, Marialuisa, Briggs, David C., Bharate, Jaideep B., Lakkaniga, Naga Rajiv, Knowles, Phillip, Wei Yan, Tran, Phuc, Kharbanda, Anupreet, Xiuqi Wang, Yuet-Kin Leung, Frett, Brendan, Santoro, Massimo, McDonald, Neil Q., Carlomagno, Francesca, Hong-yu Li |
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| Zdroj: | Journal of Medicinal Chemistry; 1/27/2022, Vol. 65 Issue 2, p1536-1551, 16p |
| Databáze: | Supplemental Index |
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