| Autor: |
Gonzalez, Michael J., Miranda-Massari, Jorge R., Duconge, Jorge, Berdiel, Miguel J. |
| Předmět: |
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| Zdroj: |
Journal of Orthomolecular Medicine; 2017, Vol. 32 Issue 1, p45-50, 6p |
| Abstrakt: |
Vitamin C has been mentioned as an agent with chemotherapeutic potential since 1952. Physiological concentrations of vitamin C (L-ascorbate or L-ascorbic acid) in the body are controlled through intestinal absorption, tissue accumulation, and renal reabsorption and excretion. Therefore, intravenous administration is used to achieve pharmacologic doses not attainable by other means. In relation to intravenous administration of ascorbate, high-dose intravenous vitamin C (>0.5 g/kg body weight) has several effects: cytotoxicity for cancer cells but not for normal cells; improved quality of life for cancer patients; protection of normal tissues from toxicity caused by chemotherapy; reinforcement of the action of radiation and some types of chemotherapy; immune system enhancement; and strengthening of collagen and hyaluronic acid. In this article we discuss important therapeutic variables that the clinician faces that are key for increasing the effectiveness of intravenous vitamin C as an anticancer agent. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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