| Autor: |
Garry, Andrew P., Flannigan, Norah L., Cooper, Lee, Komarov, Gleb, Burnside, Girvan, Higham, Sue M. |
| Předmět: |
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| Zdroj: |
Journal of Orthodontics; Sep2017, Vol. 44 Issue 3, p147-156, 10p |
| Abstrakt: |
Objective:To investigate the remineralisation of enamel subsurface lesions treated with fluoride toothpaste (1450 ppm) or a combination of fluoride toothpaste in addition to Tooth Mousse™. Design:Anin situ, cross-over, randomised controlled trial. Setting:Orthodontic department at Liverpool University Dental Hospital, UK. Participants: Twelve patients receiving fixed orthodontic treatment. Methods: Demineralised subsurface enamel lesions were placed in a carrier and attached onto a fixed orthodontic appliance. Interventions were either standard fluoride toothpaste or CPP-ACP paste (Tooth Mousse™) in addition to the fluoride toothpaste. Participants received both interventions in a randomised order. Transverse microradiography analysis was used to compare lesion mineral content profiles. Results:Mineral loss was reduced by 15.4 and 24.6% between the fluoride and CPP-ACP groups, respectively (p= 0.023). Lesion depth was reduced by 1.6 and 11.1% between the fluoride and CPP-ACP groups, respectively (p= 0.037). Lesion width was reduced by 4.5 and 15.3% between the fluoride and CPP-ACP groups, respectively (p= 0.015). Conclusions:Remineralisation occurred regardless of treatment group allocation. However, the addition of Tooth Mousse™ resulted in a significantly increased remineralisation effect, compared to fluoride alone. Tooth Mousse™ may be beneficial for patients undergoing orthodontic treatment who are at high risk of demineralisation. Trial Registration:Registered on Current Control Trialshttp://www.controlled-trials.com/ISRCTN04899524 [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
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