Clinical outcomes of switching from insulin glargine to NPH insulin in indigent patients at a charitable pharmacy: The Charitable Insulin NPH: Care for the Indigent (CINCI) study.

Autor: Curington, Russell, Espel, Mike, Heaton, Pamela C., Luder, Heidi, Brown, Bethanne
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Zdroj: Journal of the American Pharmacists Association: JAPhA; May2017:Supplement, Vol. 57 Issue 3, pS229-S235, 7p
Abstrakt: Objectives: To assess the clinical outcomes of indigent patients with type 2 diabetes served by a charitable pharmacy after therapy change from insulin glargine to NPH insulin.Design: This was a 24-week prospective pilot study.Setting: Community charitable pharmacy.Participants: Underserved, financially disadvantaged adults with type 2 diabetes.Intervention: Conversion from insulin glargine to NPH insulin.Main Outcome Measures: HbA1c, 30-day average blood glucose, number of suspected and confirmed hypoglycemic episodes, total insulin dose, and Morisky Medication Adherence Scale (MMAS) scores.Results: Patients in both control and intervention groups improved in disease-state clinical markers, safety profile, and total insulin dose. MMAS scores were unchanged.Conclusion: There were no statistically significant differences in glycemic control or hypoglycemic episodes between the control (NPH insulin) or intervention group (insulin glargine to NPH insulin). [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index