Effectiveness of Interdisciplinary vs. Dermatological Care of Moderateto-severe Psoriasis: A Pragmatic Randomised Controlled Trial.

Autor: SCHMITT, Jochen, WOZEL, Gottfried, GARZAROLLI, Marlene, VIEHWEG, Antje, BAUER, Michael, LEOPOLD, Karolina
Předmět:
Zdroj: Acta Dermato-Venereologica; 2/26/2014, Vol. 94 Issue 2, p192-197, 6p
Abstrakt: Psychiatric morbidity is frequent in patients with psoriasis. We compared the effectiveness of dermatological vs. interdisciplinary dermatological and psychiatric care for psoriasis. Adults with moderate-to-severe psoriasis were randomly allocated to dermatological (n = 24) or interdisciplinary care (n = 23) and treated accordingly. Primary endpoint was the mean change in Dermatology Life Quality Index (DLQI) at 6 months. Data was analysed by intention-to-treat. Mean ± SD change in DLQI was 7.5 ± 7.3 and 10.5 ± 9.9 after 6 months of dermatological and interdisciplinary care, respectively (p = 0.27). At baseline, 10 patients in the interdisciplinary treatment group (43%) had at least one psychiatric disorder. These patients showed significantly better DLQI response (DLQI change 14.8 ± 9.7) than patients receiving dermatological care only (p = 0.03). Ninety percent of psoriasis patients with DLQI scores exceeding psoriasis area and severity index (PASI) scores had comorbid psychiatric disease. Although psychiatric co-treatment is not generally required for patients with moderate-to-severe psoriasis, those patients with higher DLQI scores than PASI scores might benefit from interdisciplinary care. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index