| Autor: |
Lin, Zhi Mei, Yatsuhashi, Hiroshi, Daikoku, Manabu, Hamada, Rumiko, Nakao, Rumiko, Fukuda, Mika, Koga, Michiaki, Yano, Michitami |
| Předmět: |
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| Zdroj: |
Hepatology Research; Mar2003, Vol. 25 Issue 3, p244, 10p |
| Abstrakt: |
Background/aims: this study aimed to determine the viremia status after clinical, biochemical and serological recovery from acute hepatitis B viral (HBV) infection. Methods: we detected serum HBV-DNA in 19 patients with acute hepatitis B during followed-up 6–43 months after onset, and analyzed HBV genotypes. Results: 13 (72%) of 19 patients had detectable HBV DNA at the point of 6 months after onset, and four (33%) of 12 patients had persisted viremia for more than 1 year although they were recovery with normalization of alanine transaminase (ALT), disappearance of hepatitis B surface antigen (HBsAg) and appearance of antibody against HBsAg (anti-HBs). Eighteen (95%) of 19 patients were infected with HBV genotype C, one (5%) with genotype B. Conclusions: these results suggest genotype C of HBV is the predominant genotype of acute hepatitis B in Nagasaki region in Japan. HBV can persist in the serum for more than one year after complete clinical and serological recovery from acute viral hepatitis. [Copyright &y& Elsevier] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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