HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in...

Autor: Fling, Steven P., Arp, Benjamin
Předmět:
Zdroj: Nature; 4/7/1994, Vol. 368 Issue 6471, p554, 4p, 3 Black and White Photographs, 1 Chart, 21 Graphs
Abstrakt: Presents the result showing that HLA-DMA and -DMB, genes of the previously unknown function mapping between HLA-DP and HLA-DQ, are required for the normal assembly of peptides with MHC class II molecules. Encoding of subunits of a functional heterodimer by HLA-DMA and -DMB which is critical in the pathway of class II antigen presentation.
Databáze: Complementary Index