The effect of omeprazole on gastric emptying in patients with duodenal ulcer disease.

Autor: Horowitz, M, Hetzel, DJ, Buckle, PJ, Chatterton, BE, Shearman, DJ
Zdroj: British Journal of Clinical Pharmacology; 1984, Vol. 18 Issue 5, p791-794, 4p
Abstrakt: The effect of a single oral dose of omeprazole (90 mg) on gastric emptying was assessed with a dual isotope scintigraphic technique in eight patients with a history of duodenal ulcer disease. Omeprazole had no significant effect on solid or liquid gastric emptying. The bioavailability (AUC0-2 h) of omeprazole in all patients was greater than that required for total suppression of acid secretion. No adverse clinical or laboratory effects were observed. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index