| Autor: |
Park, Moon Suh, Cha, Chang, Park, M S, Cha, C I |
| Předmět: |
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| Zdroj: |
Laryngoscope; 1993, Vol. 103 Issue 2, p193-196, 4p |
| Abstrakt: |
The autologous fibrin glue (AFG) was produced from 30 human donors using the ammonium sulfate precipitation method, and a study of its biochemical composition was performed. The fibrinogen concentration ranged 13 to 57 mg/mL, the yield averaged 54.6%, and there was a direct relationship between the level of fibrinogen in plasma and AFG which had been made from the same donor's plasma. Our results suggest that the quality of this category of AFG depends partially on the fibrinogen level of donor's plasma. Quality control of the AFG is discussed. Additionally, the effectiveness of three fibrinolysis inhibitors were compared to find an optimum one which inhibits autofibrinolysis of this glue. Tranexamic acid and epsilon aminocaproic acid (EACA) were acceptable alternatives to aprotinin. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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