Correlation among Streptococcus bovis, endocarditis and septicemia in a patient with advanced colon cancer: a case report.

Autor: Abeni, Chiara, Rota, Luigina, Ogliosi, Chiara, Bertocchi, Paola, Berra Centurini, Pietro, Zaniboni, Alberto, Centurini, Pietro Berra
Předmět:
Zdroj: Journal of Medical Case Reports; 2013, Vol. 7 Issue 1, p1-3, 3p
Abstrakt: Introduction: One of the bacterial agents that has been found to be associated with colorectal cancer is Streptococcus bovis, with 13% of infective endocarditis cases caused by this pathogenic species.Case Presentation: We describe the case of a 57-year-old Caucasian man with infiltrating and ulcerating metastatic adenocarcinoma of the sigmoid colon. The patient was receiving second-line chemotherapy treatment and, on the eighth day of the second cycle, he developed a grade IV pancytopenia. We diagnosed a severe sepsis with positive blood cultures for Streptococcus bovis/gallolyticus with a secondary endocarditis.Conclusions: A recent study suggests that the majority of patients affected by colonic cancer have a Streptococcus bovis/gallolyticus colonization that becomes apparent as an overt infection only when immunosystem disorders or cardiac valve lesions occur. This correlation is important for involving more specialists in a correct and early diagnosis of this rare, but potentially fatal, complication. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index