Prediction of HIV Drug Resistance Based on Virologic, Immunologic, Clinical, and/or Adherence Criteria in the Stratall ANRS 12110/ESTHER Trial in Cameroon.

Autor: Boullé, Charlotte, Kouanfack, Charles, Laborde-Balen, Gabrièle, Aghokeng, Avelin Fobang, Boyer, Sylvie, Carrieri, Maria Patrizia, Kazé, Serge, Mben, Jean-Marc, Dontsop, Marlise, Spire, Bruno, Peeters, Martine, Mpoudi-Ngolé, Eitel, Delaporte, Eric, Laurent, Christian
Předmět:
Zdroj: Clinical Infectious Diseases; Aug2013, Vol. 57 Issue 4, p604-607, 4p
Abstrakt: Our study in Cameroonian rural district hospitals showed that the immunologic and clinical failure criteria had poor performance to identify human immunodeficiency virus drug resistance in a timely manner. Switching to second-line antiretroviral therapy after 2 consecutive viral loads ≥5000 copies/mL, as recommended by the World Health Organization, appeared to be the most appropriate strategy. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index