Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkulation damage of DNA.
| Autor: | Jiang Shou, Ali-Osman, Francis, Multani, Asha S., Pathak, Sen, Fedi, Paolo, Srivenugopal, Kalkunte S. |
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| Zdroj: | Oncogene; 1/31/2002, Vol. 21 Issue 6, p878, 12p, 8 Black and White Photographs, 9 Graphs |
| Abstrakt: | Presents information on a study that investigated the p53-related functions of the human Dkk-1 gene. Introduction to the Dkk-1 gene; Research materials and methods; Results and discussion on the study. |
| Databáze: | Complementary Index |
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