| Autor: |
Llevadot, J, Giugliano, R.P, Antman, E.M, Wilcox, R.G, Gurfinkel, E.P, Henry, T, McCabe, C.H, Charlesworth, A, Thompson, S, Nicolau, J.C, Tebbe, U, Sadowski, Z, Braunwald for the InTIME (intraenous nPA for Treatment of Infarcting Myocardium Early) II Invatigators, E |
| Zdroj: |
European Heart Journal; 2001, Vol. 22 Issue 22, p2104-2115, 12p |
| Abstrakt: |
Aims To compare management and clinical outcomes in hospitals stratified by the availability of on-site catheterization in InTIME-II, a multicentre trial comparing alteplase with lanoteplase for acute myocardial infarction.Methods and Results We studied 15–078 patients enrolled in 35 countries and 855 hospitals. Thirty-one percent of hospitals had 24-h, 25% day-only, and 44% no on-site catheterization facilities. Rates of cardiac angiography (57%, 38%, 26%) and revascularization (37%, 21%, 17%) were higher in hospitals with increasing access to on-site facilities )Conclusions There is a marked variation in procedure use by the availability of on-site catheterization with no major differences in patient outcomes. There is a need for additional randomized trials in the current era to address both the appropriate selection of patients and timing of invasive procedures in ST-elevation acute myocardial infarction. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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