| Autor: |
MOSCHOS, CHRISTOS B., OLDEWURTEL, HENRY A., LAHIRI, KAMALESH, MANSKOPF, GISBERT, REGAN, TIMOTHY J. |
| Zdroj: |
Cardiovascular Research; Nov1974, Vol. 8 Issue 6, p715-720, 6p |
| Abstrakt: |
A study was designed to evaluate scintillation images from an experimentally-induced thrombus in the anaesthetized, intact dog and explore the feasibility of detecting thrombus in the coronary artery in vivo by a non-invasive method. 131I-fibrinogen was infused systemically or into the coronary artery during the formation of a platelet thrombus with a catheter electrode. The Anger camera with pinhole collimator demonstrated only fair discrimination with systemic infusion despite substantial uptake of label in the thrombus. A clear definition of thrombus was accomplished during intracoronary infusion of isotope, largely due to the reduction of background activity from blood in the cardiac chambers. Thus, reduction of background should enable detection of a platelet thrombus in vivo, but the time limits of incorporation of label remain to be defined. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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