Moraxella catarrhalis in Acute Laryngitis: Infection or Colonization?

Autor: Hoi, C., Schalén, C., Verduin, C. M., Van Dijke, E. E. M., Verhoef, J., Fleer, A., Van Dijk, H.
Zdroj: Journal of Infectious Diseases; 1996, Vol. 174 Issue 3, p636-638, 3p
Abstrakt: The complement phenotypes of Moraxella catarrhalis isolates obtained from adult patients with acute laryngitis were investigated using a microtiter serum bactericidal assay and compared with those of other donor groups. Laryngitis isolates had a higher proportion (57%) of complement-resistant strains than did carrier strains from healthy 8- to 13-year-old schoolchildren (16%). The difference between these groups was statistically significant (χ2 [3 × 2 table] = 21.55; P < .001). The relatively frequent occurrence of the complement-resistant (virulence-associated) phenotype in adults with acute laryngitis supports the theory of an active role of M. catarrhalis in the pathogenesis of acute laryngitis. [ABSTRACT FROM PUBLISHER]
Databáze: Complementary Index