Jaundice: Cause of alarm.

Autor: Kontzoglou, K., Angelousi, A., Stefanaki, Ch., Sargedi, C., Spiridopoulou, K., Tsaknaki, S., Stamatakos, M.
Zdroj: Hellenic Journal of Surgery; Jun2012, Vol. 84 Issue 3, p160-171, 12p
Abstrakt: Background: Jaundice is the clinical manifestation of hyperbilirubinaemia, considered as a sign of either liver disease or, less often, a haemolytic disorder. It is classified as obstructive and non-obstructive, according to the increase of indirect (non-conjugated) or of direct (conjugated) bilirubin, respectively, but can also present as mixed type. Methods: This article updates the current knowledge on the aetiology of jaundice, pathophysiologic mechanisms and complications by reviewing the latest medical literature. Results: Treatment is consistent in the management of subjective diseases responsible for jaundice and its complications. Studies have shown that the severity of jaundice and the presence of malignant disease are important risk factors for postoperative mortality. Conclusions: Early detection of jaundice is of vital importance because of its involvement, both in malignancy and in benign conditions, which mandates immediate treatment to avoid further complications. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index