Predictive nature of IgM anti-α-glucose serum biomarker for relapse activity and EDSS progression in CIS patients: a BENEFIT study analysis.

Autor: Freedman, MS, Metzig, C, Kappos, L, Polman, CH, Edan, G, Hartung, H-P, Miller, DH, Montalban, X, Yarden, J, Spector, L, Fire, E, Dotan, N, Schwenke, S, Lanius, V, Sandbrink, R, Pohl, C
Předmět:
Zdroj: Multiple Sclerosis Journal; Jul2012, Vol. 18 Issue 7, p966-973, 8p, 3 Charts, 1 Graph
Abstrakt: The article presents a study which determines the prognostic value of α-glucose Immunoglobulin M (IgM) antibodies (gMS-Classfier I) in clinically isolated syndrome (CIS) patients. The study assessed the impact of early versus delayed interferon-β-Ib (IFNβ) treatment for suggestive multiple sclerosis (MS) patients. The results showed that gMS-Classfier I was not predictive of MS, but predictive of the increased risk of disability progression.
Databáze: Complementary Index