Immunohistochemical distribution of vitamin B R-binder in renal cell carcinoma.

Autor: Ogawa, Katsuhiko, Kudo, Hiroyuki, Kim, Young, Nakashima, Yasuaki, Ohshio, Gakuji, Yamabe, Hirohiko, Inada, Masami, Hamashima, Yoshihiro
Zdroj: Virchows Archiv A Pathological Anatomy & Histology; 1987, Vol. 412 Issue 1, p23-26, 4p
Abstrakt: Renal cell carcinomas and normal kidney tissues were examined for the expression of vitamin B R-binder by the indirect immunoperoxidase method. In normal kidney tissue, the presence of the vitamin B R-binder was shown to be confined to the straight portion (pars recta) of proximal tubules. Seven of the 38 cases of renal cell carcinoma (18%) expressed the vitamin B R-binder antigen. This provides a further evidence of the proximal tubular nature of renal cell carcinoma, and suggests that a small proportion of renal cell carcinomas originate from the straight portion of the renal proximal tubules. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index