| Autor: |
Lyubeznova, M., Karpeiskaya, E., Klabunovskii, E., Koreshkov, Yu., Lutsenko, A., Lubuzh, E. |
| Zdroj: |
Bulletin of the Academy of Sciences of The USSR, Division of Chemical Science; 1990, Vol. 39 Issue 4, p731-737, 7p |
| Abstrakt: |
The kinetics of aminolysis and racemization of 2-methyl-4-benzyloxazolin-5-one upon reaction with S-phenylalanine methyl ester have been studied in dimethoxyethane solvent. The rates of aminolysis and racemization are comparable. Addition of an achiral component, namely EtN, to the reaction mixture, however, dramatically increases the rate of racemization. The presence of EtN also increases the ratio of rate constants for the formation of RS- and SS-diastereomers, which determines the reaction stereoselectivity. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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