| Autor: |
Pesola, G., Akhavan, I., Madu, A., Shah, N., Carlon, G., Pesola, G R, Shah, N K, Carlon, G C |
| Předmět: |
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| Zdroj: |
Intensive Care Medicine; Jan1993, Vol. 19 Issue 1, p39-43, 5p |
| Abstrakt: |
Objective: To assess the accuracy of 4 mathematical equations used to estimate creatinine clearance versus the 24-h creatinine clearance in ICU patients.Design: Prospective study of renal function prediction.Setting: The general adult ICUs of 3 metropolitan hospitals.Patients: 199 critically ill patients with indwelling foley catheters.Intervention and Measurements: Routine 24 h creatinine clearances were evaluated only in patients whose urine volume recorded by the nurses was within 10% of the laboratory's measured volume. Four mathematical equations utilizing age, sex, body weight, height, and plasma creatinine were used as a comparison. There was no difference in estimated creatinine clearance by 3 published methods when the 24 h creatinine clearance exceeded 100 ml/min. When the 24 h creatinine clearance was less than 100 ml/min, however, one prediction equation adjusted for lean body weight (LBW), was the most accurate. This equation accurately predicted creatinine clearance in the range of 30-100 ml/min and slightly overestimated creatinine clearance at 0-30 ml/min (p < 0.01, ANOVA all groups, p < 0.05 Fisher and Scheffé post-hoc tests) with a mean difference +/- 95% confidence interval of -5 +/- 3.1 ml/min.Conclusion: An initial rapid estimate of creatinine clearance in critically ill ICU patients with reduced renal function can be determined by an equation adjusted for LBW. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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