A theoretical examination of the factors controlling the catalytic efficiency of the DNA-(adenine-N[sup 6])-methyltransferase from Thermus aquaticus.

Autor: Newby, Zachary E.R., Lau, Edmund Y., Bruice, Thomas C.
Předmět:
Zdroj: Proceedings of the National Academy of Sciences of the United States of America; 6/11/2002, Vol. 99 Issue 12, p7922, 6p, 8 Diagrams, 2 Charts, 3 Graphs
Abstrakt: Examines the factors controlling the catalytic efficiency of the DNA-(adenine-N[sup 6])-methyltransferase from Thermus aquaticus. Effect of substrate positioning on catalytic reactions; Location of the activation barrier for catalytic reactions; Details on the hydrogen bonding in N[sup 6] of adenine.
Databáze: Complementary Index