Effect of L-ornithine hydrochloride ingestion on intermittent maximal anaerobic cycle ergometer performance and fatigue recovery after exercise.

Autor:	Demura, Shinichi, Morishita, Koji, Yamada, Takayoshi, Yamaji, Shunsuke, Komatsu, Miho
Předmět:	ORNITHINE ANAEROBIC exercises FATIGUE (Physiology) AMMONIA BLIND experiment INGESTION AMINO acids ATHLETIC ability BIOCHEMISTRY CLINICAL trials COMPARATIVE studies CONVALESCENCE CROSSOVER trials CYCLES EXERCISE EXERCISE tests PHENOMENOLOGY RESEARCH methodology MEDICAL cooperation ORAL drug administration PLACEBOS RESEARCH EVALUATION research MUSCLE fatigue PHYSIOLOGY
Zdroj:	European Journal of Applied Physiology; Nov2011, Vol. 111 Issue 11, p2837-2843, 7p, 1 Diagram, 5 Graphs
Abstrakt:	L-Ornithine plays an important role in ammonia metabolism via the urea cycle. This study aimed to examine the effect of L-ornithine hydrochloride ingestion on ammonia metabolism and performance after intermittent maximal anaerobic cycle ergometer exercise. Ten healthy young adults (age, 23.8 ± 3.9 year; height, 172.3 ± 5.5 cm; body mass, 67.7 ± 6.1 kg) with regular training experience ingested L-ornithine hydrochloride (0.1 g/kg, body mass) or placebo after 30 s of maximal cycling exercise. Five sets of the same maximal cycling exercise were conducted 60 min after ingestion, and maximal cycling exercise was conducted after a 15 min rest. The intensity of cycling exercise was based on each subject's body mass (0.74 N kg(-1)). Work volume (watt), peak rpm (rpm) before and after intermittent maximal ergometer exercise and the following serum parameters were measured before ingestion, immediately after exercise and 15 min after exercise: ornithine, ammonia, urea, lactic acid and glutamate. Peak rpm was significantly greater with L-ornithine hydrochloride ingestion than with placebo ingestion. Serum ornithine level was significantly greater with L-ornithine hydrochloride ingestion than with placebo ingestion immediately and 15 min after intermittent maximal cycle ergometer exercise. In conclusion, although maximal anaerobic performance may be improved by L-ornithine hydrochloride ingestion before intermittent maximal anaerobic cycle ergometer exercise, the above may not depend on increase of ammonia metabolism with L-ornithine hydrochloride. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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