| Autor: |
Shah, R R, Evans, D A, Oates, N S, Idle, J R, Smith, R L |
| Zdroj: |
Journal of Medical Genetics; Oct1985, Vol. 22 Issue 5, p361-366, 6p, 1 Diagram, 4 Charts, 2 Graphs |
| Abstrakt: |
Previously published results of phenformin 4-hydroxylation in 195 unrelated white British volunteers and 87 family members of 27 randomly selected probands have been subjected to genetic analysis. The results clearly show that about 9% of this population has a genetically determined defect in carrying out this oxidation reaction. The character for the defect is inherited in a Mendelian autosomal recessive fashion. The polymorphism shows a substantial degree of dominance. [ABSTRACT FROM PUBLISHER] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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