Successful endoscopic therapy of superficial esophageal cancer on varices in a patient with alcoholic liver cirrhosis.

Autor: Funakoshi, Kazuhiro, Akiyama, Nobuhiro, Kozakai, Ikuo, Arai, Futoshi, Motoyama, Hirotaka, Kato, Toshiyuki, Ogoshi, Kazuei, Ohta, Tamaki
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Zdroj: Digestive Endoscopy; Dec2001, Vol. 10 Issue 4, p212-215, 4p
Abstrakt: A case of successful endoscopic therapy of superficial esophageal cancer on varices in a patient with alcoholic liver cirrhosis is reported. A slightly depressed superficial cancer (type 0-IIc) occupied half the inner surface of the middle esophagus. Endoscopic ultrasonography revealed esophageal varices and periesophageal collaterals, but no perforating veins connecting the varices and collaterals were observed where the cancer was located. The esophageal cancer could not be detected even with a 20 MHz microprobe. The tortuous esophageal varices in the lower esophagus were endoscopically ligated to reduce blood flow just below the cancer and 10 mL polidocanol solution was endoscopically injected to induce sclerosis of the varices. After these procedures, the mucosal cancer was endoscopically resected without any severe complications and residual cancer was eliminated by cauterization using a heater probe. Histopathological examination revealed that poorly differentiated squamous cell carcinoma invaded into the lamina propria mucosae but not into the vessels or the lymphatic system. Three years after treatment, the patient showed no signs of local recurrence of cancer. It is considered that the endoscopic techniques used in this patient constitute a valuable and minimally invasive treatment for superficial esophageal cancer on varices. [ABSTRACT FROM AUTHOR]
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