| Autor: |
O¿Brien, John M., Whetham, Daniel, Fecteau, Christopher, Jansen, John, Hiles, Michael |
| Předmět: |
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| Zdroj: |
American Journal of Perinatology; 2011, Vol. 28 Issue 7, p543-549, 7p, 1 Color Photograph, 1 Chart, 1 Graph |
| Abstrakt: |
We sought to reduce long-term complications after cesarean delivery by improving myometrial healing. Eight sheep (three with twins) underwent cesarean delivery. Hysterotomy sites were repaired in equal parts by suture alone or suture with a juxtaposed graft (Cook Medical, Bloomington, IN). At 90 days postsurgery, scar characteristics and tensile strength testing were assessed. The mean hysterotomy closure time was on average 1 minute, 14 seconds longer for those undergoing graft placement (p=0.36). The mean scar thickness was 3.0±0.4 mm for controls versus 3.8±1.2 mm for the intervention group (p=0.047). Tensile strength testing did not demonstrate a significant difference between groups. Histological examination of the myometrial scar showed no significant differences in inflammatory reaction or endometrial inclusions; however, neoangiogenesis was significantly enhanced. Myometrial repair incorporating a graft increased scar thickness and neoangiogenesis. This methodology did not incite adenomyosis or enhance inflammation within the scar. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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