| Autor: |
Trimble, Kara A., Clark, Richard B., Sanders, W. Eugene, Frankel, Jack W., Cacciatore, Robert, Valdez, Henry, Trimble, K A, Clark, R B, Sanders, W E Jr, Frankel, J W, Cacciatore, R, Valdez, H |
| Zdroj: |
Journal of Antimicrobial Chemotherapy (JAC); May1987, Vol. 19 Issue 5, p617-622, 6p |
| Abstrakt: |
Various clinical isolates of mycobacteria were tested for susceptibility to ciprofloxacin by a standard macrobroth dilution test and the radiometric BACTEC method. Agreement between the two test systems was species dependent: Mycobacterium tuberculosis (80%), M. kansasii with M. scrofulaceum (30%), M. avium-intracellulare (20%), and 0% for the rapidly growing mycobacteria. Most mycobacterial strains other than M. tuberculosis were susceptible to the breakpoint ciprofloxacin concentration of 2 mg/l as determined by BACTEC MICs, whereas none were susceptible by macrobroth testing. Seven of nine M. tuberculosis isolates were susceptible by either method. Ciprofloxacin merits further study as a potential antimycobacterial agent. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
